Chicken Alfredo Biscuit Casserole

This savory Chicken and Biscuit Casserole recipe includes everything you need for a hearty dinner! The ultimate comfort food, with tender chicken, broccoli, cheese, and herbed biscuits.

Taking a scoop of chicken and biscuit casserole with a wooden spoon.


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Featuring the flavors of chicken alfredo, this biscuits casserole is packed with filling and satisfying ingredients for a family favorite meal that you'll make again and again.

Ingredients Needed

Labeled ingredients for chicken and biscuit casserole.
  • Garlic: Fresh garlic works best here, but jarred minced garlic can be helpful and convenient in a pinch.
  • Half and Half: Ensures that your casserole is rich and creamy.
  • Seasonings: Thanks to nutmeg, garlic powder, Italian seasoning, and salt and black pepper, this casserole is so flavorful.
  • Cheese: Using a blend of mozzarella cheese, cheddar cheese, and Parmesan cheese ensures that your casserole is incredibly cheesy and satisfying!
  • Cooked Chicken: Using leftover chicken or a rotisserie chicken from the store is a great way to add some protein to this dish.
  • Broccoli: For some pops of vibrant green color and added nutrition.
  • Cheddar Bay Biscuit Mix: Any biscuits will work as a topping, but the cheddar bay biscuits take this casserole to the next level.
  • Milk: whole milk of 2% will work.

How to Make this Chicken and Biscuit Casserole

Steps 1 through 4 for making slow cooker chicken and biscuit casserole.
  • Step 1: In a large oven-safe skillet, melt the butter over medium-high heat.
  • Step 2: Add the garlic and saute for 30 seconds, or until fragrant.
  • Step 3: Whisk in the flour until fully incorporated.
  • Step 4: Pour in half and half, then reduce the heat to medium and simmer for 2 to 3 minutes.
Steps 5 through 8 for making chicken and biscuit casserole.
  • Step 5: Whisk in all of your seasonings.
  • Step 6: Mix in grated Parmesan cheese, stirring until smooth.
  • Step 7: Stir in broccoli, cooked chicken, and mozzarella cheese.
  • Step 8: In a separate bowl, combine the biscuit mix with cheddar cheese and milk.
Steps 9 and 10 for chicken and biscuit casserole.
  • Step 9: Drop biscuit mix by the spoonful on top of the chicken mixture.
  • Step 10: Bake at 375 for 25 to 30 minutes, or until golden brown and bubbly. Brush the biscuits with melted butter mixed with the biscuit seasoning packet.
chicken biscuit casserole in a skillet with a wooden spatula.

Recipe Tips

  • If your skillet isn't oven safe, transfer the casserole to a greased 9x13 baking dish.
  • Other vegetables like peas or diced carrots would also work well in this chicken and biscuit casserole.
  • You could even use a bag of frozen mixed vegetables and mix them right into the creamy sauce.
  • Add a little kick of heat with red pepper flakes or chili powder.
A plate of chicken and biscuit casserole.

Recipe FAQ's

Why are my biscuits dry and tough?

This often happens if you've overmixed the biscuit dough, which causes more gluten to form. Be sure to mix just until everything is combined.

Why is my casserole watery?

If the chicken or broccoli have excess liquid in them, the casserole might end up on the thinner side. Be sure you also simmer the half and half mixture long enough so it thickens up.

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Taking a scoop of chicken and biscuit casserole from a cast iron skillet.

Chicken Alfredo Biscuit Casserole

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Written By: Wendie Williams
This amazing Chicken and Biscuit Casserole is an all-in-one dinner with hearty ingredients and delicious flavors!
Prep Time 15 minutes
Cook Time 30 minutes
Total Time 45 minutes
Servings 6 servings
Calories 404

Ingredients
  

  • 3 tablespoons butter
  • 3 cloves garlic minced
  • 3 tablespoons flour
  • 2 cups half n half
  • 1 teaspoon Italian seasoning
  • 1/2 teaspoon galri cpowder
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/8 teaspoon ground nutmeg
  • 1 1/2 cups parmesan cheese
  • 3 cups cooked chicken diced
  • 2 cups broccoli chopped

Biscuit Topping

  • 1 (11 ounce) cheddar Bay biscuit mix
  • 1 cup milk
  • 1 cup cheddar cheese shredded
  • 2 tablespoons butter

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Instructions
 

  • Preheat the oven to 375 degrees
  • Heat a large 12-inch oven-safe skillet (see notes) on medium-high heat and add 2 tablespoons of butter.
  • Once melted, add in the minced garlic and cook another 30 seconds until fragrant.
  • Whisk in the flour and cook another 1-2 minutes.
  • Add in the half n half and whisk until combined, reduce the heat to medium and let simmer 2-3 minutes to thicken.
  • Whisk in the Italian seasoning, garlic powder, salt, pepper, and nutmeg until combined.
  • Add in the parmesan cheese until smooth.
  • Turn off the heat and fold in the chicken, broccoli, and shredded cheese, and set aside.

Biscuit Topping

  • In a large bowl add the biscuit mix along with the milk and cheddar cheese and mix until combined. Using a spoon drop about 10 scoops of biscuit on top of the chicken filling.
  • Bake in the center rack for 25-30 minutes or until golden brown and bubbly.
  • While the casserole is baking mix together the melted butter with the biscuit seasoning pkg.
  • Remove from the oven and brush the melted butter mixture over the biscuit. Serve!

Notes

  • If you dont have an oven-safe skillet, pour the filling into a 9x13 baking dish sprayed with non-stick cooking spray.

Nutrition

Serving: 1servingCalories: 404kcalCarbohydrates: 10gProtein: 18gFat: 33gSaturated Fat: 20gPolyunsaturated Fat: 1gMonounsaturated Fat: 9gTrans Fat: 0.4gCholesterol: 94mgSodium: 1051mgPotassium: 218mgFiber: 0.3gSugar: 6gVitamin A: 1034IUVitamin C: 1mgCalcium: 575mgIron: 1mg
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Course Entrees
Cuisine American

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